I would say by far Mother 3! and this even though I was reading some translation on gamefaq while playing in japanese. Not only the plot is very emotional, but the whole story is like some sort of critic of our society. The way I understood the message of this game was like the way we treat our natural environement (the pigs army with their manipulation of living species and New pork city) and the people we love is leading to our own destruction unless we come back to what make us really human.
Anyway, anybody played that game/ felt the same?
The sunflowers field was probably one of the most emotional moment in gaming