I've never played Fallout, any of them. However, I'm aware of a Sentinel Lyons in Fallout 3, who leads the Lyons Pride. Which I find hilarious, given that that's my family name and I have 7 siblings in my immediate family alone, so we refer to ourselves jokingly as a pride.
I found out today that my wee cousin shares her full name, but is a total skank who fights and drinks and sleeps about (she's 15!?) Why can't she be cool and play video games and be innocent and not a slut?
Anyway, gonna start using the Lyons Pride crest I think. I love it.