Snake uses cards automatically. If you have the right level, the door will open. It sounds like you and Meryl just busted out of the jjail cell and she has run off. You need to go down to the lowest floor and find some C4 and blow up certain walls to advance further.
Or, you just went to the room where Snake isn't allowed to use weapons and your nanomachines have taken that option away from you. We can help but your OP is really vague. Tell us exactly where you are and we'll get you on the right pah.








