37. 999: Nine Hours, Nine Persons, Nine Doors (2009)
Another newcomer to the list is this wonderful visual novel meets room escape game. This game uses the Nintendo DS and its medium in some of the most creative ways I've ever encountered, and surprisingly, for a story-telling purpose. Never before have I turned my handheld upside down because it made sense in the context of the story. I also loved that the story also breaks through the fourth wall to the player and gives reason for multiple playthroughs. The puzzles themselves provide a variety of interesting challenges and information. The mystery keeps you intrigued throughout the game and I was only annoyed that because I played through the route for the true ending the first playthrough I had to do the same set of doors twice.
Primarily an RPG player but have interest in any game that will make me think.