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I don't share John's taste for extravagant predictions, but it's probably safe to safe Brawl, Galaxy, and Mario Kart all have a good chance of hitting 10M sold world wide.

Galaxy is heading there at a nice pace. Should get there sometime during next year.

Brawl is looking even stronger, and will probably get there first. Launching with 800k in Japan is extremely impressive, especially since it should have much better legs than most big games there.

Nintendo has intentionally given us very little information about Mario Kart, but the previous part sold even better than the Super Mario main series game of its generation, or Melee. It could do the same this gen, but I can't help being skeptical of how it could possibly be as awesome as Brawl.