So 43 was The Curious Village. 42 is a very early PS360 game which really redefined a lot of things which are just natural in games today (for me at least), even if they weren't executed brilliantly. A sequel was released a few years later, but was not so good in my eyes. A 3rd game is due early next year.
43. Pokemon Stadium 2, N64 (2001) Nintendo/HAL Labs (Last year, 41)
This was during the height of my own personal Pokemania, and the last Colosseum type game i bought (skipping Coloseum, XD, and Battle Revolution), so it has a special place in my heart. As unbalanced as the earlier Pokemon games were, nostalgia points for all the hours spent strategizing, battling, or just dicking around with the mini-games (also the free mystery gift! And a girl to fight in that one room in Veridian!) gets this game the 41 spot.
For my 42, there is a certain game, Japan-only direct sequel to what used to be the best-selling game of all time. It was introduced to America in a 4th generation port, and also as bonus content in this game during the late 5th generation.
Monster Hunter: pissing me off since 2010.