pokoko on 11 September 2012
Pretty much impossible to name just one, so I'll list a few of my favorites instead.
Series:
Welcome to the NHK
Serial Experiments Lain
Skip Beat!
Azumanga Daioh
Steins;Gate
Chihayafuru
Monster
Nichijou
One Piece
Kare Kano
Films:
Kara no Kyoukai: Garden of Sinners (series of films)
The Girl Who Leapt Through Time
Summer Wars
Whisper of the Heart
My Neighbor Totoro
