Long, long, long story short, my gf ended 'accidentally' (as she claims to this day) erased my saved file of Pokémon Red! That totally broke me in so many ways I cannot even express. Four years of hard work with no cheat whatsoever (MissingNo, GameGenie, or GameShark, Action Replay)!
It took her a really long time for her to make it up to me, though, I'm still uncertain if I'll ever be whole again.