Your Favorite Boss Battles of All Time?

[pitzy272]

5. Spider alien creature - Resistance: FOM
4. Giant whale fish - RE4
3. Anton Gerdeux - Syphon Filter 1
2. Laughing Octopus - MGS4
1. Alden on the bridge - inFAMOUS 1

I'm sure I'm missing some major ones. Haven't played MGS2 and 3 yet, so I'm sure that would replace some here. Good topic!