How much does a game need to sell to make a profit?

[Pemalite]

Don't forget that in some countries games only need to sell half as much due to price gauging.
Not unusual for a new game to sell for $100 - $120 here in Australia if it's a AAA block buster...
And despite our dollar pretty much on parity to the US dollar we still end up paying twice as much.

Also Namco Bandai stated they needed to sell 500,000 copies of a game to turn a profit, not representative of every company and things may have changed since then, but it's figures regardless.
http://au.gamespot.com/news/6162509.html