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Depends, I suppose. If you try to talk someone out of killing themselves then yeah, do it. It is unlikely to cause you any physical harm.

On the other hand if a person put a gun to their head with the intent of blowing their brains out why should you risk your life physically trying to restrain him or her? The way I see it if that person is willing to take their own life he or she wouldn't think twice about taking yours as well.

Then again what is the person trying to top themselves to you? Relative, friend, someone you don't really know....
It all comes into it.