Cloud when Aeris died in Final Fantasy 7.
Naked Snake when he was being tortured by Ocelot in MGS3.
Solid Snake when Meryl got shot in MGS1.
Batman when he flashed back to his childhood in Arkham Asylum.
Dom when he put Maria out of her misery in Gears 2.
Old Snake being microwaved in MGS4.
John Marsden reuniting with his family in Red Dead Redemption.
Monkey when Trip set him free in Enslaved.
Samus when she was saved by the baby Metroid in Super Metroid.
The train ride in Uncharted 2 when Nate gets shot.
These are powerful moments (oh. Spoiler alert. Sorry 'bout that.) that take a game's story from standard to legendary. If you replay any of those games again, you get the same feeling you got the first time you played them. Arkham City has one (or several) of these moments. Gears 3 has a couple of these moments. Uncharted 3 didn't have one of these moments.
