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I'm personally excited by the fact that the game will feature multiple endings, including a scenario where the reapers "win." The term "galactic readiness" is kind of confusing, though. I was under the impression that you had to convince other races to fight the reapers while the invasion is going on.

What I really want to know is the whole reaper backstory.  Bioware has set up reapers so much as the ultimate antagonist, and I'm curious if any explanation will ever live up to all the hype around them.  Also, why are humans the "chosen" ones?  Surely it can't just be Shepard--maybe we're made out of tasty organic ingredients (or some equally lame reason).