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10. Scribblenauts - Interesting concept, great use of the touchscreen
9. Dragon Quest Monsters 2 - Very underrated RPG for the DS
8. Brain Age - New concept that just works, surprisingly fun and really works the mind
7. Rhythm Heaven - Very simplistic but frighteningly addictive rhythm game.
6. Yoshi's Island DS - Loved the first one on SNES, and while this one is a thousand times tougher, that's not a bad thing
5. Pokemon Diamond/Pearl - While it was largely more of the same, it's still pokemon, on the DS!
4. Big Brain Academy - similar to Brain Age, but is a little more game-based.
3. Castlevania: Order of Ecclesia - Reminds me of the old days of gaming where games were actually hard
2. NSMB - It's a new Super Mario Bros, what more needs to be said??
1. Mario Kart DS - one of the best Mario Kart games with a solid online system and tons of content