Granted some more things might be announced, but there is always going to be some overlap between years.
2007 games with no 2012 sequel planned (to the best of my knowledge)
World in Conflict
Ratchet & Clank: TOD
Uncharted
Supreme Commander
Forza 2
Unreal Tournament 3
PGR4
Metroid Prime 3
Crysis
Portal
Team Fortress 2
HL2: Episode 2
Super Mario Galaxy
Motorstorm (outside Japan)
Crackdown
Heavenly Sword
Mario Party 8 (Is 9 a 2011 or 12 game?)
Phantom Hourglass
Pokemon Diamond/Pearl
S.T.A.L.K.E.R. Shadow of Chernobyl
Enemy Territory: Quake Wars
Rock Band
Guitar Hero III (not sure if these have any 2012 versions planned, but people definitely won't care like in 2007)
Lord of the Rings Online
Stuff that hasn't been announced, but might come out in 2012.
Bound to be another Call of Duty, but probably not Modern Warfare
There will probably be another Assassin's Creed as well, but I don't think it has been announced.
Burning Crusade, once again, a good chance of another WoW expansion in 2012.
God of War II, hard to say.







