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Polyphony Digital for Sony, without a shadow of a doubt. I might reconsider once a Sony home console comes along, whose most successful first-party title isn't a Gran Turismo game.

For Nintendo, I'm not sure. Nintendo EAD Group 2, 4, and 5 (The creators of Wii Sports, the NSMB games, and Wii fit, respectively) are all invaluable.

Don't know much about Microsoft's first-party studios.