As many systems as I want? I'll only do the ones where I can name 5 without thinking too hard...
Atari 2600:
Pac-Man
E.T.
Space Invaders
Pitfall
Super Breakout
NES:
Super Mario Bros.
Duck Hunt
Legend of Zelda
Mega Man 1
Metroid
SNES:
Super Mario World
F-Zero
Donkey Kong Country
Final Fantasy 6
Star Fox
N64:
Super Mario 64
Zelda: Ocarina of Time
Conker's Bad Fur Day
Mario Kart 64
Tetrisphere
GC:
Luigi's Mansion
Metroid Prime
Tales of Symphonia
Eternal Darkness
Final Fantasy: Crystal Chronicles
Wii:
Wii Sports
Wii Fit
Mario Kart Wii
New Super Mario Bros Wii
Wii Sports Resort
Master System:
Phantasy Star
Alex Kidd
Wonder Boy
Golden Axe
Wonder Boy 3
Genesis/Mega Drive:
Sonic 1
Columns
Sonic 2
Phantasy Star 4
Mortal Kombat
Sega CD:
Sonic CD
Night Trap
Lunar 1
Shining Force CD
Lunar 2
Saturn:
Nights into Dreams
Shining Force 3
Panzer Dragoon
Guardian Heroes
Sonic R
Dreamcast:
Shenmue
Sonic Adventure
Marvel vs Capcom 2
Crazy Taxi
Chu Chu Rocket
PS1:
Final Fantasy 7
Crash Bandicoot
Tomb Raider
Castlevania: Symphony of the Night
Metal Gear Solid
PS2:
Grand Theft Auto 3
Persona 3
Final Fantasy 10
God of War
Devil May Cry
PS3:
Little Big Planet
Uncharted
God of War 3
CoD: Modern Warfare 2
Gran Turismo 5
Xbox:
Halo
Fable
Star Wars: KOTOR
Morrowind
Jade Empire
Xbox 360:
Halo 3
Fable 3
The Orange Box
Mass Effect 2
Fallout 3
Game Boy:
Tetris
Super Mario Land 2
Pokemon Red/Blue
Zelda: Link's Awakening
Final Fantasy Legend
Game Boy Color:
Pokemon Gold/Silver
Zelda: Oracle of Ages/Seasons
Kirby Tilt 'n Tumble
Zelda: Link's Awakening DX
Super Mario Bros Deluxe
Game Boy Advance:
Pokemon Ruby/Sapphire
Mother 3
Metroid Fusion
Fire Emblem
Golden Sun
DS:
Nintendogs
Brain Age
New Super Mario Bros
Dragon Quest 9
Tetris DS
3DS (tentative):
Ocarina of Time 3D
Kid Icarus: Uprising
Pilotwings Resort
AR Games
Super Street Fighter 4 3D
Game Gear:
Sonic the Hedgehog 2
Columns
Shining Force
Ristar
Land of Illusion Staring Mickey Mouse
PSP:
Crisis Core
Lumines
Patapon
echochrome
Little Big Planet
I hope that's enough for now?
