I'm not sure any game yet has really been a work of art, however four I'd consider as having come damn close, close enough to be argued as possibly works of art, are ICO, Flower, Shadow of the Colossus and Silent Hill 2.
Everything else has artistic direction but only as craftwork to design the game, not as art as its own right, or is simply a derrivative narrative or mix of elements with no clear theme.
Of course, I haven't played every game ever, but out of those I have those are the only four that felt close.
Try to be reasonable... its easier than you think...







