If it's based purely on popularity, it should be easy. IGN trends tend to follow the HD-flavor-of-the-month (currently Crysis 2, if that "most popular games" article is any indication), so all you have to do is follow the big HD multiplats, stay the hell away from Wii, DS, 3DS, and PSP, and you'll profit (you can invest in the huge stuff, like the big PS3 or Xbox exclusives or Call of Duty, but that voids the whole buy-low-sell-high game of it)
And i really think that this is an objective statement, if this whole system is based purely on popularity within the site

Monster Hunter: pissing me off since 2010.







