Timeless classics:
The Secret of Monkey Island
Monkey Island 2: LeChuck's Revenge
(both available as Special Editions on PC&Mac via Steam/PSN/XBLA/iOS)
Broken Sword: The Shadow of the Templars - Director's Cut (availabale on PC via GOG or Steam/Mac/Wii/DS)
The Longest Journey (available on PC via GOG or Steam)
4 of the best point&click adventure games ever made, 4 brilliant games for people who love story-driven games with puzzles.
Recently released on PC/360: Gray Matter
(I haven't played it yet, but it got automatic attention from point&click fans around the world because it's the new game from Jane Jensen, who's one of the few famous female designers in videogaming history)
Very useful link for people who look for great point&click/puzzle games: http://www.adventuregamers.com/recommendations.php
