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Nintendo and all its studio properties. It has made the best games ever and is credited for bringing gaming to its glory. Super Mario Bros showed the light to true 2D gamplay and Super Mario 64 for 3D perpective.  Super Mario is afterall the most well known video game icon in the world and it might be the most recognizable of any. Ocarina of Time has held a glory of being masterful and critically claimed as the best video game ever, and at that status also belongs to many Super Mario games. Sales wise it is also Nintendo. Super Mario franchise is the best selling and will remain like that forever, it seems. Then there is Pokemon who falls a bit short than the plummer but nonetheless a powerhouse indeed. Nintendo also brought in new gamers with Wii Fit franchise which will likely hit 40 million. 

If best in quality and sales than it's Nintendo.

But people have opinions, and most likely base it on their favorite franchise and what developer made it.