Changing the Pokemon formula would be a total disaster. It would piss off the fans so much.
I don't care at all about the anime. It's for little kids. Videogames are for everyone. Pokemon is a videogame first. That's what the licence truely is. The main games have to remain a RPG forever.
A-RPG, MMORPG, classic 3D would ruin the games and its popularity would suffer.