Finished college last year, topped my degree, applied for countless jobs over the year. Ended up getting a part time job that only about half the time is relevant to me degree. No matter how many jobs I applied for I couldn't get a better one until about 3 months ago where I got a second part time job working for Sony in their BR/DVD mastering department.
However I got this job through a friend from college. The world truly is about who you know, not what you know (atleast in regards to getting that foot in the door).
So now I work 2 jobs.
However I would not have gotten the second job if I hadn't been willing to take a job thats not what I wanted exactly. Without that job, my CV would have looked rubbish and I wouldn't have been able to get the job at Sony, friend or not.
My advice is take what you can get even if it isn't perfect and then use that as a springboard to get more work. And of course use your contacts if you have them!
EDIT
And having a number of friends that have been unemployed for a long time (the longest is two years now). After a while some of them kind of just gave up. Humans are emotional animals and of course actively sabotaging yourself isn't going to solve the problem, but it must be very hard to get rejection after rejection over and over again.
