45. Mario & Luigi: Bowser's Inside Story - DS
Ah, the sleeper on the list. Bowser's Inside Story has everything a Mario & Luigi game should have. It's consistently funny and self-aware, it has some great music, and taking down even the lowliest of critters is a blast. Oh, and Fawful is the most brilliant villain in the history of video games. Just saying.
"You have energy like a little angry battery with no friends."