Studio of the Year
- BioWare
- Blizzard Entertainment
- Bungie Studios
- Rockstar San Diego
Best Wii Game
- Donkey Kong Country Returns
- Kirby’s Epic Yarn
- Metroid: Other M
- Super Mario Galaxy 2
Best Xbox 360 Game
- Alan Wake
- Fable III
- Halo: Reach
- Mass Effect 2
Best PS3 Game
- God of War III
- Heavy Rain
- ModNation Racers
- Red Dead Redemption
Best PC Game
- Fallout: New Vegas
- Mass Effect 2
- Sid Meier’s Civilization V
- StarCraft II: Wings of Liberty
Best Handheld Game
- God of War: Ghost of Sparta
- Metal Gear Solid: Peace Walker
- Professor Layton and the Unwound Future
- Super Scribblenauts
Best Shooter
- Battlefield: Bad Company 2
- BioShock 2
- Call of Duty: Black Ops
- Halo: Reach
Best Action-Adventure Game
- Assassin’s Creed: Brotherhood
- God of War III
- Red Dead Redemption
- Super Mario Galaxy 2
Best RPG
- Fable III
- Fallout: New Vegas
- Final Fantasy XIII
- Mass Effect 2
Best Multiplayer Game
- Battlefield: Bad Company 2
- Call of Duty: Black Ops
- Halo: Reach
- StarCraft II: Wings of Liberty
Best Individual Sports Game
- EA Sports MMA
- Shaun White Skateboarding
- Tiger Woods PGA Tour 11
- UFC Undisputed 2010
Best Team Sports Game
- FIFA Soccer 11
- Madden NFL 11
- NBA 2K11
- MLB ’10: The Show
Best Driving Game
- Blur
- ModNation Racers
- Need For Speed: Hot Pursuit
- Split/Second
Best Music Game
- Dance Central
- DJ Hero 2
- Def Jam Rapstar
- Rock Band 3
Best Soundtrack
- Def Jam Rapstar
- DJ Hero 2
- Guitar Hero: Warriors of Rock
- Rock Band 3
Best Song in a Game
- Basket Case by Green Day
- Black Rain by Soundgarden
- Far Away by José González
- GoldenEye by Nicole Scherzinger
- Replay/Rude Boy Mashup by Iyaz & Rihanna
- Won’t Back Down by Eminem
Best Original Score
- God of War III
- Halo: Reach
- Mass Effect 2
- Red Dead Redemption
Best Graphics
- God of War III
- Heavy Rain
- Kirby’s Epic Yarn
- Red Dead Redemption
Best Adapted Video Game
- LEGO: Harry Potter: Years 1-4
- Scott Pilgrim vs. The World: The Game
- Spider-Man: Shattered Dimensions
- Star Wars: The Force Unleashed II
- Transformers: War for Cybertron
Best Performance by a Human Male
- Daniel Craig as James Bond
- Gary Oldman as Sgt. Reznov
- John Cleese as Jasper
- Martin Sheen as Illusive Man
- Nathan Fillion as Sergeant Edward Buck
- Neil Patrick Harris as Peter Parker/Amazing Spider-Man
- Rob Wiethoff as John Marston
- Sam Worthington as Alex Mason
Best Performance by a Human Female
- Dame Judi Dench as M
- Danica Patrick as Herself
- Emmanuelle Chriqui as The Numbers Lady
- Felicia Day as Veronica
- Jennifer Hale as Commander Sheppard
- Kristen Bell as Lucy Stillman
- Tricia Helfer as Sarah Kerrigan
- Yvonne Strahovski as Miranda Lawson
Best Downloadable Game
- Costume Quest
- Lara Croft and the Guardian of Light
- Monday Night Combat
- Scott Pilgrim vs. The World: The Game
Best DLC
- BioShock 2: Minerva’s Den
- Borderlands: The Secret Armory of General Knoxx
- Mass Effect 2: Lair of the Shadow Broker
- Red Dead Redemption – Undead Nightmare
Best Independent Game
- Joe Danger
- Limbo
- Super Meat Boy
- The Misadventures of P.B. Winterbottom
Most Anticipated Game
- Batman: Arkham City
- BioShock: Infinite
- Gears of War 3
- Portal 2
Game of the Year
- Call of Duty: Black Ops
- God of War III
- Halo: Reach
- Mass Effect 2
- Red Dead Redemption
