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PixelJunk Monsters
I love tower defense games. And this unique, charming tower defense game has it all. Its difficulty level is high, (for perfection), the mechanics are simple and fun, the presentation is wonderful, the music is great, as a package it is likely the most charming game I'd ever played and it has co-op. If you're at all a tower defense fan and own either a PS3 or a PSP, you really shouldn't go without playing this game.