For me it'd be:
Diablo 2 (over 1000, actually)
Pokemon Blue (over 500)
Pokemon Silver
Dragon Quest Monsters Joker
Final Fantasy 5
Final Fantasy 7
Final Fantasy Tactics
Alpha Centauri
Civilization 2
The Legend of Zelda
And soon PES 2010 and Pokemon Pearl
So, everybody, what have you played for 100 hours or more?
You do not have the right to never be offended.