Haven't played that many games lately and none really that aren't on PC/Wii/DS. So speaking partly from experience but mostly from what I've heard.
Almost certain to get some GotY:
Mass Effect 2: Perhaps not as fun as the first game, but just as epic and still completely amazing.
SMG2: This is gaming distilled. Nothing but pure blissful platforming.
Quite likely to get some GotY:
Red Dead: Heard only good things, might pick up a few GotY though there are some big contenders.
GoWIII - While not my taste in games, people who like it seem to love it =P
Unlikely but still possible:
FFXIII - Huge franchise, but was only received luke-warmly.
Heavy Rain - Heard good things, but not sure if it'll pick any up.
MHTri - From what I've heard it's more fun than what its been reviewed as. Since the GotY is retrospective it could pick some up from people who've been addicted to it for a few months =P
Of course there are some huge contenders arriving in the next half of the year.
