I had a renegade quickie with Jack... she wouldn't talk to me for the rest of the game after that. But it was cool and involved throwing lots of stuff aside.
I wanted to get it on with Miranda but didn't have enough renegade or paragon points.
After the suicide mission I invited Kelly Chamber to my personal quarters and she did a nice dance for me. If you lay in the bed she is also there besides you.
I still haven't played ME1 yet, I might do a replay of both games so I can build my paragon points up better.
Most anticipated games of 2011:
Uncharted 3,Legend of Zelda: Skyward Sword, Rocksmith
Modern Warfare 3, Super Mario 3D