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I would say that it would really depend on the nature of the application and the price range you were thinking of ...

One option would be to pick up a dual CPU motherboard and, while they are not that common, there are a couple of these motherboards designed around the i7 core for enthusiasts; and they’re in the $400 range. While I don’t have many specifics available about them, I’m fairly certain you could take one of these mother boards, combine it with 2 quad-core i5 processors, and get a decent amount of memory for less than buying one of the high-end 8-core processors.