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Wii.  Both in quality and quantity.  This is actually probably the first year it has the best lineup (over 360) imo, exclusives or not.

The Sky Crawlers: Innocent Aces 
Tatsunoko Vs. Capcom: Ultimate All-Stars 
Super Monkey Ball: Step & Roll
Endless Ocean: Blue World 
No More Heroes 2: Desperate Struggle 
Shiren the Wanderer
Fragile Dreams: Farewell Ruins of the Moon
Red Steel 2
Arcade Shooter: Ilvelo
Monster Hunter Tri
Trauma Team
Trackmania Wii (ground up Wii exclusive version)
Prince of Persia: The Forgotten Sands (ground up Wii exclusive version)
Super Mario Galaxy 2
Arc Rise Fantasia
Sin & Punishment: Star Successor
Metroid: Other M
FlingSmash
Lost in Shadow
Gunblade NY and LA Machineguns Arcade Hits Pack (1st home port for either)
Samurai Warriors 3
NBA Jam
Epic Mickey
The Conduit 2
QJ
The Legend of Zelda 
Xenoblade (most likely)
Tales of Graces (most likely)
Dragon Quest Monsters: Battle Road Victory (possibly, but more likely 2011)
The Last Story (possibly, but more likely 2011)

 

Highest quality, most diversity, and best value of all the exclusive lineups.  And this isn't even counting WiiWare stuff (Zombie Panic in Wonderland, Tomena Sanner, Bit.Trip Runner, lighttrax, Rotohex, NightSky, Q, Jett Rocket, Dive, Salamander ReBirth, Jackal ReBirth, WarioWare Showcase, etc, etc)