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FightingGameGuy said:
Powerstone I or II for the Dreamcast. Two is a bit more party oriented. In fact, I don't even remember if one has four players simultaneous.

There's also a lot of games with tag or "team" modes where you swap which player and/or character is in but don't have true multiplayer simultaneous combat.

Also, though the Worms series aren't actually fighting games (though they have 2-D gameplay and hp =D), they rock for competitive, fun, multiplayer. Instead they are a turn-based yet realtime, 2-D, wtf is going on, strategy game.

Yes, both Powerstone games had 4 player simi play.

Dead or alive 2 for Dreamcast and PS2 (with multitap) allowed for 4 players, although it was only 2 at a time. 

Clay Fighter 63 1/3 for N64 also had 4 player tag style multiplay.

Almost all Wrestling games are 4 player, although it's not really a fighting game.