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I'm on my second run through as a vanguard.

Tips for this:

1. Use the Carnifex Hand Cannon with level 1 cryo ammo, as this has 100% freeze rate on unarmoured/unshielded enemies.

2. Evolve Charge to Heavy to get the slo-mo effect.

3. Choose sniper training on the Collector Ship, not the Krogan shotgun, use the M-22 Eviscerator instead as it has better mid range.