I think Zelda Wii and Wii Relax are going to be the big releases for the second half. Other than that, I'm genuinely not sure. Nintendo could announce games from nowhere at E3 and have them released within a couple of months. I'm hoping Xenoblade makes it out in the West before year end, and something like Pikmin 3 and perhaps a Starfox/F Zero/Wave Race.
Also, whatever happened to Cosmic Walker?