Best Graphics - Mass Effect
Best Sound Effects - Mass Effect
Best Replay Value - Rock Band
Best Music/Soundtrack - Rock Band
Best Story - Mass Effect
Best Multiplayer - Halo 3
Most Innovative Feature in a Game: Portal Gun
Most Innovative Game: Portal
In specific catagories:
Best First/Third Person Shooter: Bioshock
Best Racing Game: Forza Motorsport 2
Best RPG: Mass Effect
Best Action/Adventure Game: Assassins Creed
Best XBLA Game: ?
Game of the Year (all genres): Tie: Bioshock/Mass Effect
Turd/Letdown of the Year: Blue Dragon
Feel Free To Add Me Tag: LISMDK - Extremely bad taste in music