Best Graphics - Mass Effect
Best Sound Effects - Mass Effect
Best Replay Value - Halo 3
Best Music/Soundtrack - Guitar Hero 3: Legends of Rock
Best Story - Bioshock
Most Innovative Feature in a Game: Portal Gun in Portal
Most Innovative Game: Portal
In specific catagories:
Best First/Third Person Shooter: Call of Duty 4
Best Racing Game: Forza 2
Best RPG: Blue Dragon
Best Action/Adventure Game: Assasins Creed
Best XBLA Game: Puzzle Fighter HD
Game of the Year (all genres): Bioshock
Turd/Letdown of the Year: none