I got really excited about this thread when I read part of the title: "Ubisoft: Gamer's games can succeed on Wii, RS3 coming...". Then I read the part about RS2 and realized they were talking about Red Steel and not Rainbow Six. :(
Red Steel 2 looks like a solid game that makes good use of the Wii's capabilities (both from a technical standpoint as well as the input methods). I just don't think it will fare particularly well as most of the major FPS fanatics tend to invest in their PS3's, 360's and PC's and RS2 is coming out during a pretty heavy FPS time with MW2 released just months ago and BFBC2 on its way.
I would love to see this game succeed and it's the first game that I'm even considering to get for my Wii since Zelda:TP but I just don't see it being a breakout success. I think it will be similar to Mad World where it's a great game with respectable sales but nothing outstanding when compared to sales of more family and lifestyle oriented games on the Wii.