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Squilliam said:
http://www.guru3d.com/article/vga-charts-december-2009/2

I would suggest you take a good look, especially taking note of the relative positions of the 5850 and 4890 in games where the graphs are steep as this indicates the game has a graphics bottleneck.

Also two things to take note of:

1. HD 5xxx series are DX11 which means more efficiency, better image quality etc.
2. HD 5xxx series support Eyefinity (you can use up to 6 monitors as if they are one panel) and display port for future connectivity.

Yea I keep going back to that and looking at the differences.  It is awfully tempting to just pay out the extra $100 for the card, but I'm trying to keep it under $1500 with taxes and shipping. The current list totals $1450, taxes and shipping inclusive. 

However, some components appear cheaper on this the Canada Computers site.  Can someone tell me the difference between these three cards?

MSI (R5850-PM2D1G-OC) ATI Radeon HD 5850 Chipset (765Mhz) 1GB GDDR5

HIS (H585F1GDG) ATI Radeon HD 5850 1GB GDDR5

Asus EAH5850/2DIS/1GD5/A ATI Radeon HD 5850 Chipset (725MHz )

 

Other than the manufacturer, obviously.

Some of the other components are cheaper as well, but not the CPU =(.  Might have to buy from 2 different sites to save a bit