This year is going to be one of the more split decisions that we've seen in a while (though 08 was pretty split), given that we've got the Nintendo trifecta as well as FFXIII, possibly the Last Guardian, GT5, Mass Effect 2, StarCraft II, Halo Reach, and then the inevitable candidates that just kind of come out of the woodwork (like for this year what Okami was in 06 or Arkham Asylum was last year)
It will win a few, inevitably, but there will be no consensus
Monster Hunter: pissing me off since 2010.