Mass Effect 2 of course 
But seriously,
@Epic berserk you have a HUGE back catalogue of low priced platinum / best selling titles to work through before getting into the expensive new releases. Don't even think about 2010 titles yet. Just go look at the PS3 top 100 selling games list and choose any / all of the exclusives from that list, basically you can't go wrong (filter according to genre preferences naturally). I say exclusives because I see you have a 360 so I'm sure you've already played the best multi-plat titles. Here I'll even give you a link to the list http://www.vgchartz.com/worldtotals.php?page=1&results=50&name=&console=PS3&minSales=0&publisher=&genre=&sort=Total
@ WhiteDevil I suggest you do more or less the same, though obviously filter out the ones you've played. And of course you've got all the multiplat options.
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