I'm going with no, even though I think it will cause an uptick in 360 sales for the week. I just don't think the uptick will be so substantial that it will impress people at the HW boosting effect it produces. If you want to call a game a HW seller, or even HW spiker, you've got to give HW sales a fairly hefty push.
Since there's been a comparison, Uncharted 2 didn't do PS3 any favours except in the Americas, where it gave PS3 a fairly nice 27K (34%) boost. On a worldwide basis though Uncharted 2 couldn't be called a HW mover even on it's release week. Of course PS3 was already selling better than it had all year when Uncharted 2 came out so there wasn't much room for Uncharted 2 to generate further demand. I'd be very surprised at a 30% boost from ME2.
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