Looking at people's list, I see that Jesus ranks high. I would give credit for Jesus' influence to Paul or Constantine, who gave us what we consider Christianity. Christianity as we know it today is nothing what Jesus had in mind, Jesus was a Jewish nationalist and revolutionary who wanted to liberate Israel from its Roman conquerers and build God's Kingdom (Israel) in his lifetime. Jesus actually called a woman a dog for not being a Jew and ignored her pleas to heal her sick child, saying he was only sent for Jews. It was Paul, in his successful attempt to gain more followers for his religion, who actually turned Jesus into the savior of all mankind that we know today. Also, Constatine had a heavy influence in Christianity's rise in the Roman Empire and eventually much of the world.
I'll only list a few people on my list, if I make it too big I'll start to leave people out and not rank them properly.
1. Isaac Newton - Invented calculus and discovered gravity, the scientific foundation of the modern world.
2. Julius Caesar - Created the Roman Empire, greatly influencing world history.
3. Charles Darwin - Discovered evolution, drastically changing how humans view ourselves and the world we live in.