Zelda, if it makes it. I think Mass Effect 2 will be hurt by being too early in the year. Might not be fair, but a lot of people will have forgotten about it, at least partially, by the call-in time.
Gran Turismo 5 will have a shot, being further in the year. Last Guardian if it makes it also.
Don't know how to feel about Halo Reach, but i would bet against StarCraft. They're going to do something to mess it up, to be less iconic than the original.
Monster Hunter: pissing me off since 2010.