Final Fantasy XIII - I've played all the post-SNES FF's and most of the ones before too. I pretty much grew up on the 3 PS1 FF's as a child and it's a franchise close to my heart. I'm just iffy on whether I'll be able to cope with what is supposedly ALOT of cut-scenes, as this totally put me off MGS4.
The difference is I had absolutely no ****ing clue what was happening in MGS4, but FFXIII story will hopefully be a bit more... coherent. We'll see, I don't think I'm opposed to cut-scenes mind you.
Zelda Wii - Yeah I know we know nothing about this, but I absolutely love Zelda and have played every game in the series (Except Spirit Tracks yet). Its a combination that I'm just getting jaded from Zelda, with the games really not progressing much on their basic core from the NES days. Also I found Phantom Hourglass to be poo - I guess that's the main reason I'm struggling for hype.
I'm sure it'll be okay once we get some trailers and stuff, just at the moment I'm not sure I could cope with another Zelda game that plays exactly like the other 13 I've played >_>.
Heavy Rain - It's my anti-cut scene fears coming in again. It's odd though, the game has me intriguied but I'm not sure I'll be able to stand 12 hours of it. Doubt I'll dare combine this with FFXIII anyway so will probably give it a miss :/.
That's all I could really think of, I'm quite excited for most games this year to be honest. Splendid.