I'm in the same boat as you. I picked up RE4 about 3 weeks ago. I know the previous games had way different controls and I didn't feel like back tracking through systems I might not have to play a control style I might not like.
RE:UC is great for getting the basics of the previous stories (and all kinds of nice reading material) as it covers 0, 1, and 3.
I hope they redo Resident Evil 2 with 4 controls. There has to be some reason they left out Resident Evil 2 from UC.
3rd Party Wall of Shame
http://www.nintendoworldreport.com/forums/index.php?topic=30478.msg581036#msg581036