Just lost my 360 tonight, too. Assassin's Creed killed it :( This is my 3rd RROD in 9 months.
Other than that I've been pretty lucky as far as systems go, never had one die on me.
Now computer power supplies on the other hand ...
3rd Party Wall of Shame
http://www.nintendoworldreport.com/forums/index.php?topic=30478.msg581036#msg581036