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32 bit is limlted to 4gb of memory use for each program (2GB is used by windows  so you only got 2gb left) . 64 bit uses twice the amount of space which means it's a little slower than 32 bit but 64 bit doesn't have the 4gb limit.

 A few games started to hit this 2gb limit  (this is virtual space)which causes the game to CTD after reaching the max. With 64 bit a developer has more memery  space for a program to run in.