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sapient said:

Xenosaga will probably not make sense without playing them in order.

 

However, I believe tehre is a xenosaga anime that showcases xenosaga 1. xenosaga 2 is considered  the weakest of the 3 games however.

Xenosaga 2 suffered from a different battle system as well as different voice actors.  The battle system in Xenosaga 2 isn't really that bad, but they did remove a few good things from Xenosaga 1.  The voice actors were a mixed bunch.  About the only new VA in Xenosaga 2 I liked was Chaos' VA who sounded much better in the role than the VA in Xenosaga 1.