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I do, but it seems to depend on a couple of things. One is just how I am generally feeling. Sometimes I'll be fine, other times I'll not feel well.

I believe that some of it is caused by low and choppy frame rates. It also doesn't help to be watching somebody else play a game. Take Counter-Strike for example, I play with a real high mouse sensitivity and I'll be fine, but if I were to watch somebody else with a high mouse sensitivity doing quick movements all the time, I wouldn't feel well after long.