Yes.
I've played L4D a fair bit on the 360 and it gets a bit too predictable.
This ain't something that can be fixed with a firmware patch on the 360, it's a fundamental issue of the game.
NOTE: I never bought L4D for 360 or PC (I know longer own the later, lucky my friend does), so I am a little biased. (As I haven't forked out the cash or the first one).







